The manuscript must not contain any authors’ identity revealing information. The plagiarism of any type will not be accepted. The article will be checked for plagiarism. In case of finding such high plagiarism the article will be rejected and sole responsibility will lie with author. Unless otherwise indicated, these guidelines are in accordance with “Uniform Requirements for Manuscripts submitted to Biomedical Journals”.

PRESENTATION AND GENERAL FORMATTING
• Language: American English
• Font Type: Times New Roman
• Font size: 12 points
• Margin: Uniform margin of 2.5 cm (inch) from all sides
• Spacing: Double spacing in text
• Page numbers at the bottom right side
• No indents for paragraphs
• Justified text
• No colons/hyphens/dashes after headings
• All numbers less than 10 (except in case of % or as part of name) to be spelled out.
• Sentences should not begin with numbers. If unavoidable, then the number should be spelled out.
• Abbreviations should be mentioned completely at their first use in the text

TITLE

The Title should be concise and informative. Titles are often used in information-retrieval systems. Avoid abbreviations and formulae where possible.

ABSTRACT

The abstract should be typed on a separate page for original article and should not exceed 250 words. The abstract can be structured or unstructured. It should briefly state the purpose of the research, the methodology used, the principal results and major conclusions. An abstract is often presented separately from the article, so it must be able to stand alone. For this reason, references should be avoided. Also, non-standard or uncommon abbreviations should be avoided, but if essential, they must be defined at their first mention in the abstract itself. Use American spelling and avoid use of general and plural terms, multiple concepts (for example, 'and', 'of').

KEYWORDS

The abstract should be followed by a maximum of 6 key words. (These keywords will be used for indexing purposes.)

INTRODUCTION

It should start from general terms and then gradually describe the specific topic. It should describe the research gap and the need of the study. It should end with the aims and specific objectives. Abbreviations used should be defined at their first mention. It should be about 20% of total word limit of the article.

MATERIAL AND METHODS

The standard guidelines like STROBE, CONSORT, PRISMA, STARD, should be followed for writing paper as per study design. The reporting guidelines for different study designs are available at https://www.equator-network.org/reporting-guidelines/.

This section should include sub-headings as follows for original articles:
• Type of study- Observational or interventional
• Study design - Cohort, Case-control, Cross-sectional, Qualitative, Randomized Control Trial etc.
• Study location/site
• Study period
• Participants and inclusion/exclusion criteria
• Sample size estimation and sampling method
• Variables and operational definitions- Outcome variables and all other selected variables with their operational definitions should be mentioned. All the units of measurements should be internationally accepted.
• Data collection tools
• Data collection procedure and quality checks
• Data analysis- Tests/statistical operations used

The Materials and Methods section should not reveal identify the institution(s) where the work was performed.

RESULTS/ OBSERVATIONS

Results should be presented in a logical sequence and depict the major findings or observations of the study. Avoid duplication of data in text and tables or figures. Results/ Observations can include following sub-headings:

• Population - Describing the sample population and the demographic characteristics in brief
• Outcome - Describe the outcome
• Associated factors- Describe the associated variables/ risk factors- The statistical tests used should be mentioned. The actual P value should be written below the result/observation. If table is given, statistical test and P value should be included along with table.

Refer the tables or figures in text in numerical order as they appeared. Tables should be given at the end after reference, on separate page for each table.

DISCUSSION

It is expected that most of the discussion should revolve around your observations. Whenever sensitive or controversial or shocking/appalling statements are made, they should be supported by proper references. The author must substantiate the findings with appropriate reasons.Strengths and limitations with regards to study design, data collection, data analysis and interpretation, generalizability of the findings, bias can be mentioned in discussion or separately.

CONCLUSIONS

The implication of the study should be mentioned as the conclusion

RECOMMENDATIONS

Recommendations if any, may be described

REFERENCES

• Please refrain from using end notes as references or automatic list numbering because these features are lost in conversion.
• Reference numbers in the text should follow numerical order. It should be enclosed in parentheses ( ) and superscripted, followed by a punctuation mark as ⁽¹⁾, or ⁽²⁾.
• The reference style used by this journal is Vancouver numbered. Journal names should be abbreviated according to the List of Title Word Abbreviations. e.g. Kurman RJ, Shih IeM. The Dualistic Model of Ovarian Carcinogenesis: Revisited, Revised, and Expanded. Am J Pathol. 2016 Apr;186(4):733-47.
• The reference style used by this journal will be applied to the accepted article by the publisher at proof stage.
• Please ensure that every reference cited in the text is also present in the reference list (and vice versa).
• Unpublished results and personal communications are not recommended in the reference list, but may be mentioned in the text. If these references are included in the reference list they should follow the standard reference style of the journal and should include a substitution of the publication date with either 'Unpublished results' or 'Personal communication'.
• Citation of a reference as 'in press' implies that the item has been accepted for publication.
• Authors preferably refrain from quoting references more than 15 years old.
• Use of the Digital Object Identifier services (DOI) is encouraged. A DOI can be used to cite and link to electronic articles where an article is in-press and full citation details are not yet known, but the article is available online. A DOI is guaranteed never to change, so you can use it as a permanent link to any electronic article.
• Please note the format of such citations should be in the same style as all other references in the paper.
• Web References: The complete web address (URL) should be given mentioning; (Available at https://...........……………………………………) .Then the date of last access should be mentioned as; (Accessed on: 1 February 2020). Any further information, if known, (DOI, author names, dates, reference to a source publication, etc.) should also be given. For standard details authors are requested to refer; https://www.nlm.nih.gov/bsd/uniform_requirements.html.

TABLES

• Be sparing in the use of tables and ensure that the data presented in them do not duplicate results described elsewhere in the article.
• All tables must be numbered sequentially in Arabic numerals in the order of their citation in the text.
• The table should be accompanied by a clear and specific title at the top of the table centrally placed. The title should be self-explanatory. (E.g. Table 5: Incidence of pneumonia among children in Pune District, India in 2016-17). The title should be in bold.
• Table notes can be placed below the table body as footnotes and symbols like *, # can be used to explain.
• Each table should be typed double-spaced on a separate sheet of paper placed at the end after references.
• Please submit tables as editable text and not as images.
• The table should not have vertical lines or shading cells.

FIGURE LEGENDS AND CAPTIONS

• Number the figures/ illustrations in Arabic numerals according to their sequence in the text.
• Submit each figure legend i.e. figure title on a separate page at the end of the manuscript after tables.
• Provide captions to illustrations separately after the figure legend.
• Please mention the source of figure if applicable.

DISCLAIMER IF ANY

• If a disclaimer is required it should be written on a separate page at the end of the manuscript.